Myeloid spatial and transcriptional molecular signature of ischemia-reperfusion injury in human liver transplantation.
Rebecca A SosaRichard AhnFang LiAllyson Q TerryZach QianAdil BhatSubha SenBita V NainiTakahiro ItoFady M KaldasRebecca A SosaRonald W BusuttilJerzy W Kupiec-WeglinskiDavid W GjertsonElaine F ReedPublished in: Hepatology communications (2024)
Myeloid subset-specific genes and related signaling pathways provide targets for the development of therapeutic strategies aimed at limiting IRI in the clinical setting of liver transplantation.
Keyphrases
- dendritic cells
- bone marrow
- endothelial cells
- acute myeloid leukemia
- signaling pathway
- induced pluripotent stem cells
- genome wide
- gene expression
- transcription factor
- pluripotent stem cells
- pi k akt
- epithelial mesenchymal transition
- immune response
- bioinformatics analysis
- dna methylation
- induced apoptosis
- drug induced