Menopausal hormone therapy and the female brain: leveraging neuroimaging and prescription registry data from the UK Biobank cohort.

Claudia Barth Liisa A M Galea Emily G JacobsBonnie H LeeLars Tjelta Westlye Ann-Marie Glasø de Lange

Published in: medRxiv : the preprint server for health sciences (2024)

Our results indicate that population-level associations between MHT use, and female brain health might vary depending on duration of use and past surgical history. Future research is crucial to establish causality, dissect interactions between menopause-related neurological changes and MHT use, and determine individual-level implications to advance precision medicine in female health care.

Keyphrases

healthcare
resting state
white matter
public health
functional connectivity
health information
electronic health record
emergency department
big data
multiple sclerosis
cross sectional
machine learning
climate change
adverse drug
social media
deep learning
bone marrow
health promotion
cell therapy