Integrated re-analysis of transcriptomic and proteomic datasets reveals potential mechanisms for Zika viral-based oncolytic therapy in neuroblastoma.
Matthew SherwoodYilu ZhouYi SuiYihua WangPaul SkippCarolini KaidJuliet GrayKeith OkamotoRob M EwingPublished in: F1000Research (2024)
Our work provides a significant understanding of ZIKV infection in neuroblastoma cells, which will facilitate the progression of ZIKV-based oncolytic virotherapy through pre-clinical research and clinical trials.
Keyphrases
- zika virus
- clinical trial
- induced apoptosis
- dengue virus
- cell cycle arrest
- rna seq
- aedes aegypti
- sars cov
- single cell
- endoplasmic reticulum stress
- stem cells
- signaling pathway
- randomized controlled trial
- cell death
- oxidative stress
- human health
- cell proliferation
- mesenchymal stem cells
- label free
- bone marrow
- climate change