Longitudinal assessment of physical function in adults with X-linked hypophosphatemia following initiation of burosumab therapy.
Giorgio OrlandoMatthew RoyJudith BubbearShane ClarkeRichard KeenMuhammad Kassim JavaidAlex IrelandPublished in: Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA (2024)
Burosumab treatment is associated with improved lower limb function and mobility at 6 months, with improvement in hand grip strength at 12 months. Future studies should explore the underlying mechanisms and describe on function and other patient outcomes.