Jabuticaba peel extract modulates adipocyte and osteoblast differentiation of MSCs from healthy and osteoporotic rats.
Alann Thaffarell Portilho SouzaGileade Pereira FreitasHelena Bacha LopesGabriela Guaraldo Campos TotoliAdriana Gadioli TaroneMário Roberto MarósticaAdalberto Luiz RosaAdalberto Luiz RosaPublished in: Journal of bone and mineral metabolism (2020)
Our results demonstrated that JPE drives MSCs to inhibit adipocyte differentiation and toward osteoblast differentiation under healthy and osteoporotic conditions. These findings pave the way for further translational studies to investigate the therapeutic possibilities of JPE in both prevention and treatment of osteoporosis.