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Pragmaticism of Randomized Controlled Trials of Biologic Treatment With Methotrexate in Rheumatoid Arthritis: A Systematic Review.

May Yee ChoiCheryl C M BarnabeClaire E BarberVivian BykerkJanet E PopeGlen S Hazlewood
Published in: Arthritis care & research (2019)
RCTs of biologic DMARD treatment in combination with methotrexate for RA were rated as predominantly explanatory, which may affect the generalizability of trial results to clinical practice.
Keyphrases
  • rheumatoid arthritis
  • clinical practice
  • disease activity
  • clinical trial
  • study protocol
  • randomized controlled trial
  • african american
  • open label