Review article: long-term safety of oral anti-viral treatment for chronic hepatitis B.

Grace Lai-Hung Wong Wai Kay Seto Vincent Wai-Sun Wong Man Fung Yuen Henry Lik Yuen Chan

Published in: Alimentary pharmacology & therapeutics (2018)

Long-term safety profile of nucleoside analogues is now better defined with more data from large real-life cohorts and clinical trials with long-term follow-up. The new nucleotide analogue, TAF is now available with favourable renal and bone safety profiles.

Keyphrases

clinical trial
hepatitis b virus
bone mineral density
electronic health record
randomized controlled trial
big data
machine learning
body composition
postmenopausal women
artificial intelligence
soft tissue
molecular dynamics simulations
phase ii
smoking cessation