In vitro effect of granulocyte-macrophage colony-stimulating factor (GM-CSF) on the expression of genes related to sperm motility and energy metabolism and intracytoplasmic sperm injection outcomes in obstructive azoospermic patients.
Samaneh AghajanpourElham HosseiniFatemeh Sadat AmjadiMasoud MohammadianZahra ZandiehFarnaz MohammadianRaheleh KafaeinezhadMahnaz AshrafiPublished in: Molecular biology reports (2024)
GM-CSF increased the expression of genes related to motility and the energy metabolism pathway and effectively promoted the motility of testis-extracted spermatozoa, consequently yielding positive clinical outcomes.
Keyphrases
- poor prognosis
- biofilm formation
- end stage renal disease
- genome wide
- ejection fraction
- newly diagnosed
- prognostic factors
- peritoneal dialysis
- binding protein
- escherichia coli
- pseudomonas aeruginosa
- dna methylation
- long non coding rna
- metabolic syndrome
- genome wide identification
- transcription factor
- patient reported outcomes
- skeletal muscle
- genome wide analysis
- germ cell