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Relationships among Postprandial Plasma Active GLP-1 and GIP Excursions, Skeletal Muscle Mass, and Body Fat Mass in Patients with Type 2 Diabetes Treated with Either Miglitol, Sitagliptin, or Their Combination: A Secondary Analysis of the MASTER Study.

Masahiro SatoHiroki FujitaHiroki YokoyamaAtsushi MikadaYohei HorikawaYuya TakahashiYuichiro YamadaHironori WakiTakuma Narita
Published in: Journal of clinical medicine (2023)
Collectively, although T2D patients treated with miglitol and/or sitagliptin did not show altered SMI after 24-week treatment, the current study suggests that there are possible interrelationships among postprandial plasma aGIP excursion modified by sitagliptin, skeletal muscle mass, and body fat mass.
Keyphrases
  • randomized controlled trial
  • metabolic syndrome
  • clinical trial
  • blood glucose
  • skeletal muscle
  • adipose tissue
  • glycemic control
  • smoking cessation
  • combination therapy