Photoresponsive host-guest chemistry and relaxation time of fluorinated cyclodextrin and arylazopyrazole-functionalized DOTA metal complexes.
Julian SimkeTill BöckermannKlaus BerganderSina KlabundeMichael Ryan HansenBart Jan RavooPublished in: Organic & biomolecular chemistry (2021)
Light-responsive modulation of the longitudinal (T1) and transversal relaxation times of a fluorinated cyclodextrin has been achieved by host-guest complexation with arylazopyrazole-modified metal complexes in aqueous solution. This supramolecular concept can potentially be applied to the development of contrast agents for 19F magnetic resonance imaging (MRI).
Keyphrases
- magnetic resonance imaging
- aqueous solution
- contrast enhanced
- water soluble
- magnetic resonance
- single molecule
- computed tomography
- ionic liquid
- capillary electrophoresis
- diffusion weighted imaging
- pet ct
- pet imaging
- cancer therapy
- quantum dots
- cross sectional
- molecularly imprinted
- drug delivery
- positron emission tomography