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Effects of Moderate Exercise Training on Cancer-Induced Muscle Wasting.

Ana Cristina Corrêa FigueiraAna Fátima PereiraLuís Filipe Moutinho LeitãoRita FerreiraPaula Alexandra OliveiraJosé Alberto Duarte
Published in: Healthcare (Basel, Switzerland) (2023)
In sedentary animals with tumors, the gastrocnemius muscle showed a very pronounced reduction in cross-sectional area and a marked degree of interstitial fibrosis. There was no difference in collagen deposition between tumor groups, and the soleus muscle showed a less pronounced but significant reduction in cross-sectional area. These contrasting results confirm that cancer-induced muscle wasting can affect specific types of fibers and specific muscles, namely fast glycolytic muscles, and that exercise training can be used to improve it.
Keyphrases
  • skeletal muscle
  • cross sectional
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  • high glucose
  • diabetic rats
  • physical activity
  • squamous cell carcinoma
  • wound healing
  • liver fibrosis