Protective parents and permissive children: what qualitative interviews with parents and children can tell us about the feasibility of juvenile idiopathic arthritis trials.
Frances C SherrattLouise RoperSimon R StonesFlora McErlaneMatthew PeakMichael W BeresfordHelen FosterAthimalaipet V RamananMadeleine RooneyEileen BaildamBridget YoungPublished in: Pediatric rheumatology online journal (2018)
Previous research has typically focused on deficits in patients' understandings of trials. We found that both parents and CYP understood trial concepts and were able to identify potential flaws in the proposed trial. We propose recommendations to optimise the design of a planned corticosteroid induction regimen trial in JIA. Accessing both parents' and CYP's perspectives helps to identify and address recruitment challenges, which will ultimately optimise informed consent and future recruitment.
Keyphrases
- juvenile idiopathic arthritis
- phase iii
- study protocol
- phase ii
- clinical trial
- end stage renal disease
- young adults
- chronic kidney disease
- ejection fraction
- traumatic brain injury
- peritoneal dialysis
- randomized controlled trial
- prognostic factors
- systematic review
- open label
- risk assessment
- clinical practice
- human health
- climate change
- double blind