Genomic and transcriptomic analysis of breast cancer identifies novel signatures associated with response to neoadjuvant chemotherapy.

Gengshen YinLiyuan LiuTing YuLixiang YuMan FengChengjun ZhouXiaoying WangGuoxin TengZhongbing MaWenzhong ZhouChunmiao YeJialin ZhangChanghua JiLinfeng ZhaoPeng ZhouYaxun GuoXingchen MengQinye FuQiang ZhangLiang LiFei ZhouChao ZhengYujuan XiangMingming GuoYongjiu WangFei WangShuya HuangZhi-Gang Yu

Published in: Genome medicine (2024)

, ADGRA2 and ADRB3) underlying chemotherapy resistance and poor prognosis, which could guide the development of personalized treatments for BC.

Keyphrases

poor prognosis
neoadjuvant chemotherapy
locally advanced
long non coding rna
genome wide
rectal cancer
squamous cell carcinoma
sentinel lymph node
lymph node
radiation therapy
copy number
dna methylation
gene expression
childhood cancer