Prevalence of asthma, aspirin sensitivity and allergy in chronic rhinosinusitis: data from the UK National Chronic Rhinosinusitis Epidemiology Study.
Carl M PhilpottSally ErskineClaire HopkinsNirmal KumarShahram AnariNaveed KaraSankalp SunkaraneniJaydip RayAllan ClarkAndrew Wilsonnull nullSally ErskineCarl Martin PhilpottAllan ClarkClaire HopkinsAlasdair RobertsonShahzada AhmedNaveed KaraSean CarrieVishnu SunkaraneniJaydip RayShahram AnariPaul JervisJaan PanesaarAmir FarboudNirmal KumarRussell CathcartRobert AlmeydaHisham KhalilPeter PrinsleyNicolas MansellMahmoud SalamJonathan HobsonJane WoodsEmma CoombesPublished in: Respiratory research (2018)
The prevalence of asthma and allergy in CRS varies by phenoytype, with CRSwNPs and AFRS having a stronger association with both. Aspirin sensitivity has a highly significant association with AFRS. All of these comorbidities are significantly more prevalent than in non-CRS controls and strengthen the need for a more individualised approach to the combined airway.
Keyphrases
- chronic rhinosinusitis
- risk factors
- low dose
- chronic obstructive pulmonary disease
- lung function
- cardiovascular events
- allergic rhinitis
- antiplatelet therapy
- atopic dermatitis
- quality improvement
- electronic health record
- big data
- cross sectional
- cardiovascular disease
- infectious diseases
- machine learning
- deep learning
- anti inflammatory drugs