Moderation of baclofen response by a GABAB receptor polymorphism: results from the BacALD randomized controlled trial.

Kirsten C MorleyNatasha LuquinAndrew J BaillieIsabel FraserRonald J TrentGlenys DoreNghi PhungPaul S Haber

Published in: Addiction (Abingdon, England) (2018)

The GABBR1 rs29220 polymorphism may influence treatment response and possibly predict adverse effects to baclofen in the treatment of alcohol dependence.

Keyphrases

randomized controlled trial
study protocol
systematic review
clinical trial
combination therapy
alcohol consumption
replacement therapy