A Systematic Review and Network Meta-Analysis on the Efficacy of Medications in the Treatment of Chronic Idiopathic Constipation in Japan.

Hirokazu Takahashi Ayako ShojiKinya KokuboAtaru Igarashi

Published in: Gastroenterology research and practice (2021)

Our direct and indirect meta-analyses revealed that the new CIC medications available in Japan have equal efficacy but that elobixibat and lubiprostone are highly likely to be more efficacious.

Keyphrases

meta analyses
systematic review
randomized controlled trial
single cell
irritable bowel syndrome
replacement therapy