Oral Vancomycin Prophylaxis for Primary and Secondary Prevention of Clostridioides difficile Infection in Patients Treated with Systemic Antibiotic Therapy: A Systematic Review, Meta-Analysis and Trial Sequential Analysis.
Alberto Enrico MaraoloMazzitelli MariaEmanuela ZappuloRiccardo ScottoGuido GranataRoberto AndiniEmanuele Durante-MangoniNicola PetrosilloGentile IvanPublished in: Antibiotics (Basel, Switzerland) (2022)
OVP appears to be an efficacious option for prevention of CDI in high-risk subjects undergoing SAT. Nevertheless, additional data from RCTs are needed to establish OVP as good clinical practice and define optimal dosage and duration.