Pre-clinical evaluation of the efficacy and safety of human induced pluripotent stem cell-derived cardiomyocyte patch.

Shigeru MiyagawaTakuji KawamuraEmiko ItoMaki TakedaHiroko IseokaJunya YokoyamaAkima HaradaNoriko Mochizuki-OdaYukiko Imanishi-OchiJunjun LiMasao SasaiFumiyo KitaokaMasaki NomuraNaoki AmanoTomoko TakahashiHiromi DohiEiichi MoriiYoshiki Sawa

Published in: Stem cell research & therapy (2024)

hiPSC-CM patches are promising for future translational research and may have clinical application potential for the treatment of heart failure.

Keyphrases

clinical evaluation
heart failure
high glucose
endothelial cells
diabetic rats
current status
left ventricular
drug induced
oxidative stress
pluripotent stem cells
climate change
cardiac resynchronization therapy
smoking cessation