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Regulation of nuclear mTORC1.

Xin ZhouYanghao ZhongJin Zhang
Published in: Molecular & cellular oncology (2021)
mTORC1 integrates diverse upstream signals to control cell growth and metabolism. We previously showed that mTORC1 activity is spatially compartmentalized to ensure its signaling specificity. In a recently published study, we demonstrated the existence of mTORC1 activity in the nucleus and identified a unique mode of its regulation in the nuclear compartment.
Keyphrases
  • randomized controlled trial
  • meta analyses