The Notch Pathway in Breast Cancer Progression.

Emmanuel N KontomanolisSofia KalagasidouStamatia PouliliouXanthoula AnthoulakiNikolaos GeorgiouValentinos PapamanolisZacharias N Fasoulakis

Published in: TheScientificWorldJournal (2018)

Current data prove that Notch pathway has a major participation and multiple roles during breast tumor progression. Inhibition of Notch receptors and ligands provides innovative therapeutic results and could become the therapy of choice in the next few years, even though further research is needed to reach safe conclusions.

Keyphrases

cell proliferation
poor prognosis
physical activity
big data
stem cells
machine learning
decision making
bone marrow
deep learning
breast cancer risk