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Shorter and Longer Courses of Antibiotics for Common Infections and the Association With Reductions of Infection-Related Complications Including Hospital Admissions.

Victoria PalinWilliam WelfareDarren M AshcroftTjeerd Pieter van Staa
Published in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America (2021)
Equal effectiveness was found between shorter and longer antibiotic courses and the reduction of infection-related hospitalizations. Stewardship programs should recommend shorter courses of antibiotics for acute infections. Further research is required for treating patients with a complex medical history.SummaryPrescribing of longer courses increased over the study period. The majority of hospitalizations occurred for patients receiving longer courses. Risk of developing a complication (immediate vs remaining follow-up) found longer courses were no more effective than shorter courses.
Keyphrases
  • randomized controlled trial
  • public health
  • risk factors
  • liver failure
  • drug induced
  • hepatitis b virus
  • extracorporeal membrane oxygenation