Mechanisms of Pathogenicity of Hypertrophic Cardiomyopathy-Associated Troponin T (TNNT2) Variant R278C +/- During Development.

Sanam ShafaatalabAlison Y LiFarah JayousiYasaman MaarefSaif DababnehHoma HamledariDina Hosseini BaygiTiffany BarszczewskiBalwinder RupraiShayan JannatiRaghu NagalingamAustin M CoolPaulina LangaMu ChiaoThomas RostonR John SolaroShubhayan SanataniChristopher ToepferSteffen Lindert Philipp F Lange Glen F Tibbits

Published in: bioRxiv : the preprint server for biology (2023)

hiPSC-CMs, positing it as a potential therapy for thin filament HCM.

Keyphrases

hypertrophic cardiomyopathy
left ventricular
human health
biofilm formation
risk assessment
atrial fibrillation