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Effectiveness of Medical Cannabis for the Treatment of Depression: A Naturalistic Outpatient Study.

Michael SpeckaUdo BonnetLisa SchmidbergJulian WichmannMartin KellerChristian ScholzeNorbert Scherbaum
Published in: Pharmacopsychiatry (2024)
Medical cannabis was well tolerated and dropout rate was comparable to those in clinical trials of antidepressant medication. Patients reported a clinically significant reduction of depression severity. Further research on the effectiveness of medical cannabis for MDD seems warranted. Risks of this medication, such as sustaining or inducing a cannabis use disorder, or side effects such as poor concentration, must be taken into consideration.
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