Management of antithrombotic therapy in patients undergoing transcatheter aortic valve implantation: a consensus document of the ESC Working Group on Thrombosis and the European Association of Percutaneous Cardiovascular Interventions (EAPCI), in collaboration with the ESC Council on Valvular Heart Disease.
Jurrien M Ten BergDirk SibbingBianca RoccaEric Van BelleBernard ChevalierJean Philippe ColletDariusz DudekMartine GilardDiana Adrienne GorogJulia GrapsaErik Lerkevang GrovePatrizio LancellottiAnna Sonia PetronioAndrea RubboliLucia TorraccaGemma VilahurAdam WitkowskiJulinda MehilliPublished in: European heart journal (2021)
Transcatheter aortic valve implantation (TAVI) is effective in older patients with symptomatic severe aortic stenosis, while the indication has recently broadened to younger patients at lower risk. Although thromboembolic and bleeding complications after TAVI have decreased over time, such adverse events are still common. The recommendations of the latest 2017 ESC/EACTS Guidelines for the management of valvular heart disease on antithrombotic therapy in patients undergoing TAVI are mostly based on expert opinion. Based on recent studies and randomized controlled trials, this viewpoint document provides updated therapeutic insights in antithrombotic treatment during and after TAVI.
Keyphrases
- transcatheter aortic valve implantation
- atrial fibrillation
- aortic stenosis
- aortic valve
- aortic valve replacement
- patients undergoing
- transcatheter aortic valve replacement
- ejection fraction
- clinical practice
- left ventricular
- oral anticoagulants
- randomized controlled trial
- pulmonary hypertension
- heart failure
- physical activity
- coronary artery disease
- pulmonary embolism
- early onset
- stem cells
- minimally invasive
- clinical trial
- radiofrequency ablation
- study protocol
- systematic review