The Impact of Type 2 Diabetes in Parkinson's Disease.

Dilan AthaudaJames EvansAnna WernickGurvir VirdiMinee L ChoiMichael LawtonNirosen VijiaratnamChristine GirgesYoav Ben-ShlomoKhalida IsmailHuw MorrisDonald GrossetThomas FoltynieSonia Gandhi

Published in: Movement disorders : official journal of the Movement Disorder Society (2022)

In the largest study to date, T2DM is associated with faster disease progression in Parkinson's, highlighting an interaction between these two diseases. Because it is a potentially modifiable metabolic state, with multiple peripheral and central targets for intervention, it may represent a target for alleviating parkinsonian symptoms and slowing progression to disability and dementia. © 2022 The Authors. Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society.

Keyphrases

type diabetes
randomized controlled trial
glycemic control
mild cognitive impairment
multiple sclerosis
insulin resistance
physical activity
metabolic syndrome