Optical imaging of pre-invasive breast cancer with a combination of VHHs targeting CAIX and HER2 increases contrast and facilitates tumour characterization.
Marta M KijankaAram S A van BrusselElsken van der WallWillem P T M MaliPaul J van DiestPaul M P van Bergen En HenegouwenSabrina OliveiraPublished in: EJNMMI research (2016)
These results establish the feasibility of the use of VHH 'cocktails' to increase T/B ratios and improve early detection of heterogeneous tumours and the use of multispectral molecular imaging to facilitate the assessment of the target expression status of tumours and metastases, both invasive or non-invasively.