Ether lipids, sphingolipids and toxic 1-deoxyceramides as hallmarks for lean and obese type 2 diabetic patients.
J Thomas HannichUrsula Loizides-MangoldFlore SinturelTakeshi HarayamaBart VandereyckenCamille SainiPauline GosselinMarie-Claude Brulhart-MeynetMaud RobertStephanie ChanonChristine DurandJonathan Paz MontoyaFabrice P A DavidIdris GuessousZoltan PatakyAlain GolayFrançois R JornayvazJacques PhilippeEmmanouil T DermitzakisSteven A BrownEtienne LefaiHoward RiezmanCharna DibnerPublished in: Acta physiologica (Oxford, England) (2021)
Taken together, the observed lipidome changes in obesity and T2D will facilitate the identification of T2D patient subgroups and represent an important step towards personalized medicine in diabetes.