Dual-Modality Imaging of the Human Finger Joint Systems by Using Combined Multispectral Photoacoustic Computed Tomography and Ultrasound Computed Tomography.
Yubin LiuYating WangZhen YuanPublished in: BioMed research international (2016)
We developed a homemade dual-modality imaging system that combines multispectral photoacoustic computed tomography and ultrasound computed tomography for reconstructing the structural and functional information of human finger joint systems. The fused multispectral photoacoustic-ultrasound computed tomography (MPAUCT) system was examined by the phantom and in vivo experimental tests. The imaging results indicate that the hard tissues such as the bones and the soft tissues including the blood vessels, the tendon, the skins, and the subcutaneous tissues in the finger joints systems can be effectively recovered by using our multimodality MPAUCT system. The developed MPAUCT system is able to provide us with more comprehensive information of the human finger joints, which shows its potential for characterization and diagnosis of bone or joint diseases.
Keyphrases
- computed tomography
- fluorescence imaging
- magnetic resonance imaging
- positron emission tomography
- endothelial cells
- dual energy
- high resolution
- image quality
- gene expression
- induced pluripotent stem cells
- contrast enhanced
- pluripotent stem cells
- photodynamic therapy
- ultrasound guided
- bone mineral density
- health information
- bone loss