Waning intra-season vaccine effectiveness against influenza A(H3N2) underlines the need for more durable protection.

Alexander DomnichAndrea OrsiAlessio SignoriMaria ChironnaIlaria ManiniChristian NapoliCaterina RizzoDonatella PanattoGiancarlo Icardi

Published in: Expert review of vaccines (2024)

Significant waning of VE, especially against influenza A(H3N2), may be one of the factors associated with suboptimal end-of-season VE. Next-generation vaccines should provide more durable protection against A(H3N2).

Keyphrases

randomized controlled trial
systematic review