IVF versus IUI with ovarian stimulation for unexplained infertility: a collaborative individual participant data meta-analysis.
Shimona LaiRui WangMadelon van WelyMichael CostelloCindy FarquharAlexandra J BensdorpInge M CustersAngelique J GoverdeHossam ElzeinyBen-Willem J MolWentao LiPublished in: Human reproduction update (2023)
There is no robust evidence that in couples with unexplained infertility IVF achieves pregnancy leading to live birth faster than IUI-OS. IVF and IUI-OS are both viable options in terms of effectiveness and safety for managing unexplained infertility. The associated costs of interventions and the preference of couples need to be weighed in clinical decision-making.
Keyphrases
- pregnancy outcomes
- systematic review
- decision making
- polycystic ovary syndrome
- pregnant women
- meta analyses
- electronic health record
- physical activity
- quality improvement
- preterm birth
- big data
- machine learning
- insulin resistance
- randomized controlled trial
- metabolic syndrome
- skeletal muscle
- artificial intelligence