Evaluation of microRNA Expression Features in Patients with Various Types of Arterial Damage: Thoracic Aortic Aneurysm and Coronary Atherosclerosis.
Ange Veroniqe Ngo Bilong EkediAndrey N RozhkovDmitry Yu ShchekochikhinNina A NovikovaPhilippe Yu KopylovAfina A BestavashviliTatiana V IvanovaAndrey V ZhelankinEdward V GenerozovDmitry N KonanovAnna S AkselrodPublished in: Journal of personalized medicine (2023)
TAA and CAD patients demonstrated a significant increase in the levels of circulating miR-126-5p/-3p, miR-181b-5p, and miR-29b-3p. More specific for TAA with very high predictive ability in ROC analysis was an increase in the levels of miR-21-5p, -29b-5p, -126-5p/-3p, 181b-5p, and -92a-3p, with the latter microRNA being investigated as a potential marker of TAA for the first time.
Keyphrases
- end stage renal disease
- coronary artery disease
- aortic aneurysm
- ejection fraction
- chronic kidney disease
- newly diagnosed
- poor prognosis
- coronary artery
- spinal cord
- oxidative stress
- peritoneal dialysis
- prognostic factors
- heart failure
- type diabetes
- aortic stenosis
- risk assessment
- atrial fibrillation
- human health
- climate change
- high resolution
- left ventricular
- transcatheter aortic valve replacement
- patient reported