The quantity and quality of cardiovascular fat at mid-life and future cognitive performance among women: The SWAN cardiovascular fat ancillary study.
Meiyuzhen QiImke JanssenEmma Barinas-MitchellMatthew BudoffMaria M BrooksArun S KarlamanglaCarol A DerbyChung-Chou H ChangKelly J ShieldsSamar R El KhoudaryPublished in: Alzheimer's & dementia : the journal of the Alzheimer's Association (2023)
Higher mid-life thoracic perivascular adipose tissue (thoracic PVAT) volume is related to a better future episodic memory in women. Higher mid-life thoracic PVAT radiodensity is related to worse future working and episodic memories. Negative association of high thoracic PVAT radiodensity with working memory is prominent at higher thoracic PVAT volume. Mid-life thoracic PVAT is linked to future memory loss, an early sign of Alzheimer's disease. Mid-life women's epicardial and paracardial fat are not related to future cognition.