Repair of Cranial Defects in Rabbits with 3D-Printed Hydroxyapatite/Polylactic Acid Composites.

Guofeng Fan Liu Yang Dong Liu Yongxin Wang Wenyu Ji Tukebai Hu Qin Zengliang Wang

Published in: BioMed research international (2022)

3D-printed HA-PLA composites can induce bone regeneration, are biocompatible, have the same strength as autologous bone powder, are able to degrade, and are ultimately safe and effective for repairing cranial defects in rabbits. However, further research is needed to determine the feasibility of 3D-printed HA-PLA composites in human cranioplasty.

Keyphrases

bone regeneration
reduced graphene oxide
endothelial cells
visible light
aqueous solution
bone marrow
gold nanoparticles
induced pluripotent stem cells
pluripotent stem cells
cell therapy
drug release
bone mineral density
drug delivery