A prospective study examining the expression of STAT 1, 3, 6 in prurigo nodularis lesions with its immunopathogenic and therapeutic implications.

Diksha AgrawalKabir Sardana Sinu Rose MathachanMinakshi BhardwajArvind AhujaSwasti Jain

Published in: Journal of cosmetic dermatology (2021)

Our study showed a marked dominance of STAT 3 and STAT 6 staining in the epidermis which signifies that the keratinocytes play an important role in PN and suggest that Th2, Th17, and Th22 cytokines mediate the tissue response in PN.

Keyphrases

cell proliferation
poor prognosis
long non coding rna
flow cytometry
wound healing