Pharmacokinetic evaluation of [18F]PR04.MZ for PET/CT imaging and quantification of dopamine transporters in the human brain.

Vasko KramerCarlos JuriPatrick J RissRossana PruzzoCristian Soza-RiedJonathan FloresAna HurtadoFrank RöschPedro Chana-CuevasHoracio Amaral

Published in: European journal of nuclear medicine and molecular imaging (2019)

[18F]PR04.MZ is a PET tracer with very high affinity, selectivity, and specific uptake in striatum and midbrain. 2TCM and SRTM provide good fits, high and stable Vts or BPnds, and good test-retest reliability for precise quantification of DAT in human subjects.

Keyphrases

pet ct
positron emission tomography
endothelial cells
high resolution
computed tomography
induced pluripotent stem cells
pluripotent stem cells
uric acid