Fetal teratogenicity in a rhesus macaque (Macaca mulatta): Association with the chronic maternal treatment of amitriptyline.

Carissa E HunterRachelle L StammenTerell HamletDenise BonenbergerChunxia LiXiaodong ZhangFawn C StroudAnthony W S Chan

Published in: Journal of medical primatology (2020)

Amitriptyline is a tricyclic antidepressant commonly prescribed in humans for pain and sleep disorders and in non-human primates for self-injurious behaviors. Here, we report a clinical case on the teratogenic effect of maternal-fetal amitriptyline exposure.

Keyphrases

birth weight
endothelial cells
pregnancy outcomes
chronic pain
pain management
sleep quality
pregnant women
depressive symptoms
pluripotent stem cells
gestational age
combination therapy
spinal cord injury
drug induced
weight loss