Hereditary transthyretin amyloidosis in middle-aged and elderly patients with idiopathic polyneuropathy: a nationwide prospective study.

Guillaume FargeotAndoni Echaniz-LagunaCéline LabeyrieJuliette SvahnJean-Philippe CamdessanchéPascal CintasJean-Baptiste ChansonFlorence EsselinCéline PiedvacheCéline VerstuyftSteeve GenestetEmmeline LagrangeLaurent MagyYann PéréonSabrina SacconiAissatou SignateAleksandra Nadaj-PaklezaFrédéric TaitheKarine VialaCéline TardVianney PoinsignonCécile CauquilShahram AttarianDavid Adams

Published in: Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis (2023)

In this nationwide prospective study, we found ATTRv in 2.7% of patients with age >50 years with a progressive polyneuropathy. These results are highly important for the early identification of patients in need of disease-modifying treatments.

Keyphrases

end stage renal disease
newly diagnosed
ejection fraction
chronic kidney disease
multiple sclerosis
cross sectional
prognostic factors
multiple myeloma
patient reported
bioinformatics analysis