Investigation of stemness and multipotency of equine adipose-derived mesenchymal stem cells (ASCs) from different fat sources in comparison with lipoma.
Stefan ArnholdMohamed I ElashryMichele C KlymiukFlorian GeburekPublished in: Stem cell research & therapy (2019)
The results provide evidence of variation in ASC performance not only between normal fat depots but also compared to LP cells which suggest a different molecular regulation controlling the cell fate. These data provided are useful when considering a source for cell replacement therapy in equine veterinary medicine.
Keyphrases
- replacement therapy
- cell fate
- adipose tissue
- induced apoptosis
- smoking cessation
- stem cells
- cell cycle arrest
- single cell
- fatty acid
- electronic health record
- epithelial mesenchymal transition
- drinking water
- insulin resistance
- cell therapy
- endoplasmic reticulum stress
- signaling pathway
- big data
- cell death
- oxidative stress
- mesenchymal stem cells
- nlrp inflammasome
- cell proliferation
- deep learning
- pi k akt
- cancer stem cells