Evaluation of osteogenic induction potency of miR-27a-3p in adipose tissue-derived human mesenchymal stem cells (AD-hMSCs).
Fatemeh ArabSeyed Hamid Aghaee BakhtiariAlireza PasdarEhsan SaburiPublished in: Molecular biology reports (2022)
Our data suggest that miR-27a-3p may positively regulates adipose tissue-derived mesenchymal stem cell differentiation into bone by targeting APC and activating the Wnt/b-catenin pathway.
Keyphrases
- adipose tissue
- mesenchymal stem cells
- bone marrow
- insulin resistance
- stem cells
- umbilical cord
- endothelial cells
- high fat diet
- cell proliferation
- signaling pathway
- electronic health record
- bone mineral density
- big data
- pluripotent stem cells
- machine learning
- metabolic syndrome
- postmenopausal women
- soft tissue
- deep learning
- data analysis