Development of a [89Zr]Zr-labeled human antibody using a novel phage-displayed human scFv library.
Abhay Kumar SinghCalvin D LewisCristian A W V BoasPhilipp DiebolderPrashant N JethvaAaron J RheeJong Hee SongYoung Ah GooShunqiang LiMichael L NickelsYongjian LiuBuck E RogersVaishali KapoorDennis E HallahanPublished in: Clinical cancer research : an official journal of the American Association for Cancer Research (2024)
L111 Ab targets lung cancer cells in vitro and in vivo. [89Zr]Zr-DFO-L111 is a human antibody that will be evaluated in the first-in-human study of safety and PET imaging.