Cocoa Shell Aqueous Phenolic Extract Preserves Mitochondrial Function and Insulin Sensitivity by Attenuating Inflammation between Macrophages and Adipocytes In Vitro.

Miguel Rebollo-HernanzQiaozhi ZhangYolanda AguileraMaria A Martín-CabrejasElvira Gonzalez de Mejia

Published in: Molecular nutrition & food research (2019)

CAE phenolics promote a beige phenotype in adipocytes. Macrophages-adipocytes inflammatory interaction is reduced preventing mitochondrial dysfunction and insulin resistance. For the first time, CAE shows a positive effect on adipogenesis and inflammation-related disorders.

Keyphrases

oxidative stress
adipose tissue
high fat diet induced
insulin resistance
high fat diet
metabolic syndrome
skeletal muscle
ionic liquid
anti inflammatory
glycemic control