Improvement of bone microarchitecture in methylprednisolone induced rat model of osteoporosis by using thiolated chitosan-based risedronate mucoadhesive film.

Dhrubojyoti MukherjeeBharath SrinivasanJ AnbuMohammad AzamthullaVenkatesh Teja BanalaS G Ramachandra

Published in: Drug development and industrial pharmacy (2018)

The results significantly suggest that risedronate loaded novel mucoadhesive film formulation could be a logical approach in the therapeutic intervention of osteoporosis.

Keyphrases

bone mineral density
drug delivery
postmenopausal women
room temperature
reduced graphene oxide
randomized controlled trial
body composition
wound healing
cancer therapy
diabetic rats
high glucose
high dose
drug induced
oxidative stress
bone loss
hyaluronic acid
soft tissue
gold nanoparticles