Prostanoid receptor genes confer poor prognosis in head and neck squamous cell carcinoma via epigenetic inactivation.

Kiyoshi MisawaMasato MimaYamada SatoshiAtsushi ImaiDaiki MochizukiRyuji IshikawaJunya KitaYuki YamaguchiShiori EndoYuki MisawaHiroyuki Mineta

Published in: Journal of translational medicine (2020)

We characterised the relationship between the methylation status of prostanoid receptor genes and recurrence in HNSCC. These results provide new perspectives for the development of molecular targeted treatment approaches.

Keyphrases

poor prognosis
genome wide
long non coding rna
dna methylation
gene expression
bioinformatics analysis
genome wide identification
binding protein
free survival
replacement therapy