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Association of mild kidney dysfunction with diastolic dysfunction and heart failure with preserved ejection fraction.

Robin W M VernooijAnne-Mar L N van OmmenGideon B ValstarMaarten Jan CramerArco J TeskeRoxana MenkenLeo HofstraFrans H RuttenMichiel L BotsHester M den RuijterMarianne C Verhaar
Published in: ESC heart failure (2023)
Both mild and moderate kidney dysfunction are independently associated with left ventricular diastolic dysfunction parameters and HFpEF. This association is independent of sex and strongest for moderate kidney dysfunction. Considering mild-to-moderate kidney dysfunction as risk factor for HFpEF may help identify high-risk groups benefiting most from early intervention.
Keyphrases
  • left ventricular
  • oxidative stress
  • randomized controlled trial
  • heart failure
  • blood pressure
  • hypertrophic cardiomyopathy
  • left atrial
  • transcatheter aortic valve replacement