Histrelin Implantation and Growth Outcomes in Children With Congenital Adrenal Hyperplasia: An Institutional Experience.

Robert A Swendiman Barbara E CoonsCraig A AlterVaneeta BambaMichael L NanceMaria G Vogiatzi

Published in: Journal of the Endocrine Society (2019)

In this retrospective cohort study of children with CAH due to 21OHD and early or precocious puberty, histrelin implantation resulted in a decrease in BA progression compared to CA and an improvement in PAH. In the subgroup who completed growth, adult height remained significantly lower than midparental. These results need to be confirmed with prospective controlled studies.

Keyphrases

young adults
body mass index
randomized controlled trial
metabolic syndrome
adipose tissue
skeletal muscle
study protocol