Maternal and perinatal outcomes of SARS-CoV-2 infection in unvaccinated pregnancies during Delta and Omicron waves.
P Birol IlterSmriti PrasadM A MutluA B TekinP O'BrienP von DadelszenLaura Ann MageeS TekinN TugErkan KalafatAsma KhalilPublished in: Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology (2022)
Among unvaccinated pregnant women, SARS-CoV-2 infection during the Delta wave, in comparison to the pre-Delta period, was associated with increased requirement for oxygen support (including ECMO) and higher maternal mortality. Disease severity and pregnancy complications were similar between the Omicron wave and pre-Delta period. SARS-CoV-2 infection of unvaccinated pregnant women carries considerable risks of morbidity and mortality regardless of variant, and vaccination remains key. Miscommunication of the risks of Omicron infection may impact adversely vaccination uptake among pregnant women, who are at increased risk of complications related to SARS-CoV-2. © 2022 The Authors. Ultrasound in Obstetrics & Gynecology published by John Wiley & Sons Ltd on behalf of International Society of Ultrasound in Obstetrics and Gynecology.
Keyphrases
- pregnant women
- pregnancy outcomes
- respiratory syndrome coronavirus
- sars cov
- risk factors
- magnetic resonance imaging
- human health
- preterm birth
- birth weight
- extracorporeal membrane oxygenation
- acute respiratory distress syndrome
- cardiovascular events
- cardiovascular disease
- computed tomography
- risk assessment
- intensive care unit
- gestational age
- climate change
- coronary artery disease
- randomized controlled trial