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Chemoimmunotherapy Versus Pembrolizumab as a First-Line Treatment for Patients with Advanced Non-small Cell Lung Cancer and High PD-L1 Expression: Focus on the Role of Performance Status.

Kenji MorimotoTadaaki YamadaHayato KawachiMotohiro TamiyaYoshiki NegiYasuhiro GotoAkira NakaoShinsuke ShiotsuKeiko TanimuraTakayuki TakedaAsuka OkadaTaishi HaradaKoji DateYusuke ChiharaIsao HasegawaNobuyo TamiyaNaoya NishiokaYuki KatayamaMasahiro IwasakuShinsaku TokudaTakashi KijimaKoichi Takayama
Published in: Targeted oncology (2023)
In patients with NSCLC exhibiting poor PS and high PD-L1 expression, ICI plus chemotherapy did not confer PFS or OS benefit compared with pembrolizumab monotherapy.
Keyphrases
  • advanced non small cell lung cancer
  • epidermal growth factor receptor
  • small cell lung cancer
  • clinical trial
  • randomized controlled trial
  • locally advanced
  • study protocol
  • rectal cancer
  • chemotherapy induced