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Efficacy of propylthiouracil in the treatment of pregnancy with hyperthyroidism and its effect on pregnancy outcomes: A meta-analysis.

Yiqun MiaoYang XuPing TengAihua WangYuanyuan ZhangYun ZhouWenwen Liu
Published in: PloS one (2022)
This meta-analysis confirmed the beneficial effects of propylthiouracil treatment, namely the risks of adverse pregnancy outcomes were not increased, and it also proved PTU's efficacy in the treatment of pregnant women with hyperthyroidism. The findings supported the use of propylthiouracil during pregnancy with hyperthyroidism in order to improve clinical pregnancy outcomes in patients with thyroid dysfunction.
Keyphrases
  • pregnancy outcomes
  • pregnant women
  • systematic review
  • emergency department
  • randomized controlled trial
  • combination therapy
  • meta analyses
  • replacement therapy