Effect of diet supplemented with African Star Apple Fruit Pulp on purinergic, cholinergic and monoaminergic enzymes, TNF-α expression and redox imbalance in the brain of hypertensive rats.
Tosin A OlasehindeSeun F AKomolafeIyabo F OladapoSunday Idowu OyeleyePublished in: Nutritional neuroscience (2022)
This study demonstrates the neuroprotective role of FP supplemented diet against alterations in neurochemicals associated with Alzheimer's disease, oxidative stress-induced neuronal damage and expression of genes linked with neuroinflammation. Moreover, studies on animal behaviour and human subjects are required to confirm these beneficial effects.
Keyphrases
- cerebral ischemia
- poor prognosis
- physical activity
- weight loss
- endothelial cells
- rheumatoid arthritis
- subarachnoid hemorrhage
- binding protein
- oxidative stress
- traumatic brain injury
- genome wide
- lipopolysaccharide induced
- cognitive decline
- brain injury
- multiple sclerosis
- induced pluripotent stem cells
- lps induced
- genome wide identification
- mild cognitive impairment
- functional connectivity