Pancreatic Enzyme Use Reduces Pancreatitis Frequency in Children with Acute Recurrent or Chronic Pancreatitis: A report from INSPPIRE.
Alvin Jay FreemanKenneth NgFuchenchu WangMaisam A Abu-El-HaijaAnkur ChughGretchen A CressDouglas S FishmanCheryl E GariepyMatthew J GieferPraveen GodayTanja Y GonskaAmit S GroverDouglas LindbladQuin Y LiuAsim MaqboolJacob A MarkBrian A McFerronMegha S MehtaVeronique D MorinvilleRobert A NoelChee Yee OoiEmily R PeritoSarah Jane SchwarzenbergZachary M SellersMichael WilschanskiYuhua ZhengYing YuanDana K AndersenMark E LoweAliye Ucnull nullPublished in: The American journal of gastroenterology (2024)
In a retrospective analysis, use of PERT was associated with a reduction in the incidence rate of AP among children with pancreatic sufficient ARP or CP. These results support the need for a clinical trial to evaluate the efficacy of PERT to improve clinical outcomes among children with ARP or CP.